appreciate it very much. that's it for me here in d.c., watch fox news sunday when we'll be talking with senator saxby chambliss. make it a great day. thanks for watching. . [sirens] . [sirens] >> well, a fox news alert, everyone, that's how many people in israel are spending their day today as the sirens blare across israel. as the country's military shoots down a rocket that was bound for the heavily populated city of tel aviv, that happened during a fourth straight day of escalating violence with gaza. hi, everyone, i'm jamie colby, welcome to america's news headquarters, good to see you.

>> kelly: good to see you, jamie. you hear the sirens and we're just glad it's not happening at home. just ma'am if it's happening to your home. israel tapping into the massive military defense arsenal right now. launching its iron dome rocket defense system to intercept one of the hundreds of missiles fired into israeli air space. and this is video capturing the very moment the iron dome struck down a rocket aimed at tel aviv. you can hear people on the ground applauding. and there is word that israel is now mobilizing as many as 75,000 troops in preparation for a possible invasion of the gaza strip. adding to the sea of tanks and troops at that are now on stand by near the border with gaza, leland vittert is live on the front lines near the israel-gaza border, leland? >> reporter: kelly, we're in front of what would be the tip of israel's spear, the black behind me, where the tanks would roll through on the gaza strip and the lights behind

me. right now as we speak, we're hearing explosions inside the gaza strip, the sound of israeli drones and f-16's overhead and every once in a while a red dot fly out of gaza. that's one of the missiles headed out of gaza toward the millions of israeli civilians now in the line of fair. israel's ground forces are just waiting for the go order, the d-9 bulldozers that will lead the assault over-the-hill into gaza and then you have the tanks and armored personnel carriers that will follow in, we were at this position just 24 hours ago, there is significantly more activity. they have fuel trucks brought in, ammunition trucks brought in to supply the troops that are just waiting for the go order. through the afternoon, gaza militants launched countless rocket volleys, one towards tel aviv, and sirens sent beach goers running for cover. the iron dome system intercepted it before it could

hit the city. but it doesn't always work that way. this home video captured a rock hitting an apartment building. taking refuge in a bomb shelter saved those eating lunch here from certain death. right now, there are cease-fire talks going on in cairo, the head of hamas and islamic jihad, a number of negotiators through the egyptians who then talk to the israelis about cease-fire terms. the idea here going forward would be sometime 24 to 48 hours, in order to prevent that ground war, that's if they can get a cease-fire in place and at that point we would know whether we're going to a ground war which could last weeks or perhaps longer or if both sides call it a day and more in their debt and of course, civilian casualties on both sides. >> kelly: we hope the cease-fire takes place, we know the military is prepared and what they train for, what about the civilians living in

israel. hearing those sirens go off. you can only imagine what it's like to hear sirens going off, not knowing if a rocket is going to strike your home, your place of business, or even the beach front where you're enjoying a time with your family. what's the atmosphere, the mood among the civilians there? >> over the past couple of days, this country has gone from its sort of joyful normal self to all of a sudden on a war footing. anyone in the americas who hasn't experienced the sound of air raid sirens, the first time you do, your heart rate goes through the roof and now all of a sudden as it happens you start looking around at times like this, okay, i'm driving down the street, which sidewalk would i run to to take shelter, is there a wall somewhere, the entrance to a building somewhere, everyday life for the 1 million israelis who live within the core threat of these rockets. this didn't just start four days ago, for weeks, months now every couple of days from ground zero came the rockets,

and completely disrupted lives and put millions of lives at risk and why the israelis finally took the step of escalating things, killing one of the top hamas commanders and the head of their military wing, either the rocket fire stops or we're going into the ground. >> kelly: leland vittert, as you've mentioned there have been civilian casualties on both sides which is regrettable. how the conflict unfolded. 70 rockets landed inside israel not including the 25 rockets intercepted by israel's iron dome. since the start of israel's operation of civil defense, over 400 rockets, mortars and missiles hit hundreds more have been intercepted as well. how does the iron dome missile defense work? for one, it's able to calculate each rocket's trajectory and only intercept those that will hit a target and this is done through a vast array of sensors located

around the country which determine whether a rocket is expected to land into a populated area or not. >> jamie: meanwhile, the white house today is reiterating that israel, quote, as a right to defend itself defense any attacks and the top two aides of president obama or top aide i should say, also telling reporters that the u.s. and israel both want an end to the rocket fire. that's coming from the gaza strip. president obama has also spoken to the leaders of egypt and turkey, and the administration feels they have the ability to encourage hamas to end this violence. >> and while this situation in the mideast develops, president obama is on his way to southeast asia. deputy national security advisor ben rhodes says working with that region will be a critical part of the president's second term, and ultimately his foreign policy legacy. president obama will first arrive at thailand before moving on to cambodian and then on monday, he will make history by becoming the first

sitting u.s. president to visit myanmar. >> jamie: and the white house is now reporting that president obama has set up a meeting with congressional leaders the week after thanksgiving. no doubt they will discuss how to avoid the fiscal cliff. that's a series of automatic tax hikes and spending cuts due to kick in the beginning of next year. at that point the tax rates are expected to be a sticking point in the negotiations because both sides have already made their case to the american people, listen. >> the other path is for congress to pass a law right away to prevent a tax like on the first $250,000 of anyone's income. and that means all americans, including the wealthiest americans get a tax cut and 98% of americans and 97% of iness owners won't see their income taxes go up a single dime. the senate has already passed a bill like this, democrats in the house are ready it pass one, too. all we need is for republicans in the house to come on board. we shouldn't hold the middle

class hostage while congress debates tax cuts for the wealthy. >> tax reform that eliminates wasteful tax to generate revenue will help bring fairness and efficiency to our tax system and this approach makes more sense than raising tax rates, which will harm nearly a million small businesses and cost hundreds of thousands of jobs. >> as a reminder, just two years ago, president obama said that raising taxes would be unwise given the weakness of our recovery. that's as true now as it was then. >> jamie: well, joining us now are fox news political analyst, angela mcglowan and former clinton pollster, doug schoen also a fox news contributor. great to see you. >> great to see you. >> jamie: doug, do you predict it will have end results or finger pointing? >> we're certainly getting

enough finger pointing already, jamie, but i hope that it ends, as i think every american does, in a deal. but, reading between the lines of the meeting yesterday, they have a two part frame work to try to get a short-term agreement now and a longer term agreement on tax reform and spending and entitlement reform next year, but i don't hear any agreement as the sound bites suggested on quite how to do it and unless we can come to quick agreement about how we change our tax system in the short-term, we literally head over the fiscal cliff and make what i believe are a number of unwise tax increases and spending cuts that i arguably could sends us back into recession. >> jamie: interestingly, a big group that's going to be hit hard by it is elderly and if you're thinking of retiring, you'll want to stay tuned. what is the road map, angela for averting the fiscal cliff, is there one? >> there is one, being down in

d.c. i'm actually sighing the senate and housework. if obama, president obama and boehner cannot come up with a plan the past two years, you have senators, a gang of six actually working on a plan b. so if boehner and obama can't come up with something that can go through the house you have a bipartisan group of senators working together, even bob corker from tennessee is working on a bill that will help simplify the code. if plan a doesn't work, plan b will work because at the end. day the american people have spoken, they kept the senate the same, the house virtually the same and the same president, so they're giving them a second chance to actually have our system work. and if working a bipartisan way, it will work. >> jamie: doug, the president, having not submitted a budget that passed in the first four years, at this point are there numbers out there that anybody has seen that proves that the tax increases and the spending cuts will avert a fiscal cliff? >> well, i think the immediate

challenge is to avoid what's been called sequestration which is the process in place when they did the debt ceiling deal over a year ago. so, i think there's got to be an agreement, but to your specific question, jamie, the democrats have numbers saying that we've got to raise rates. the republicans say you can do it without raising rates. so there are two sets of numbers on both sides and despite angela's optimism, which i hope is born out, i see no evidence to suggest that we have any agreement on either a frame work or numbers. >> jamie: so, angela, is there a compromise? could you envision a compromise? both sides coming together and if not, can the president take action on his own during a lame duck session, for example? >> well, nancy pelosi seems to think, as she was mixed up with the 11th and 14th amendment in raising the debt ceiling, the congress and the president needs to work together, but as for numbers,

the congressional budget office came out with a recent report saying if you do what republicans want to do, it will only have the economy grow 1.5%, if you do what obama wants us to do, 1.25%, so, jamie, for it to actually come to a compromise, it just can't be a discussion about tax increases or not. you're going to have to cut spending and have entitlement reform. so, i do believe that they're going to go to a compromise, either speaking of the fiscal cliff and hurting seniors. if we go over the fiscal cliff, it will hurt all americans. >> jamie: i understand, thank you both so much for weighing in. great discussion, doug schoen and angela mcglowan, angela the optimist. (laughter) >> good to see you, it was an extremely tight election, over now in arizona, barber has won the 2nd congressional district narrowly beating out the republican. and the voters had picked barbara to fill out the

remainder of gabrielle giffords term. last week the election was so tight it took them to pick a clear winner. >> a fallout from the david petraeus scandal, the head of the briefing lawmakers on capitol hill behind closedtors, in an attempt to answer questions about the deadly attack on the u.s. consulate in libya that killed four americans. but na briefing only raising more questions than answers today. our molly henneberg is live in d.c. with more details, molly, what's going on. >> reporter: kelly, we have new information this hour, the white house now responding to questions about the cia talking points that were given to administration officials and lawmakers in the days and weeks right after the attack in libya. some republicans have been asking who edited those talking points? to promote the idea that the attack was the result of a violent mob protesting an anti-muslim video, and to take out the reference to an al-qaeda-linked terror attack? and instead mention extreme

organizations. the white house says, don't look at them. the white house deputy national security advisor ben rose told reporters today, quote, the only edit that was made by the white house and also by the state department was to change the word consulate to the word diplomatic facility. the facility in benghazi, libya was not formally a consulate. the cia talking points went through numerous hands, various intelligence agencies, the white house, state department, justice department, before going out to lawmakers. former cia director general david petraeus told members of congress yesterday in a hearing, he was not sure who approved the final version, but republicans say they want to track down an answer. . >> we have to find it out. find out what the motives were, what the reasons, where it was done, how it was done and again, what, you know, what prompted them to do it because clearly the intelligence community had it right. somewhere along the ryan, the policy makers changed it.

>> reporter: republicans contend the obama administration want today change the talking points for political reasons, to downplay presence of terrorists in libya. democrats say the edits were made to protect classified information and keep al-qaeda in the dark about what we knew about the attack. kelly. >> kelly: all right. molly, thank you for that report. >> molly, thank you as well. we're going to have much more on the benghazi hearings coming up at the bottom of the hour, we will talk to a member of the house intelligence committee who has been in on some of those hearings. >> kelly: indeed we will. and admitting to a major flaw in airline security. just ahead, what it means for passenger safety. >> jamie: so close to holiday travel, too, and two rock icons, using star power to raise awareness about teenagers, that are fighting cancer. you don't want to miss this. we'll be right back.

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♪ >> a quick check of the headlines now. a bus carrying kindergarteners to school hit by a train in southern egypt and reports say close to 50 people have been

killed, so tragic. and the coast guard is searching for two missing workers after a fire eruption on an oil platform in the gulf of mexico and at least four other workers hospitalized with critical injuries. and a small plane crashing in maine killing all aboard. officials say the plane struck a tree on the runway and went down. down. >> in today's installment of beyond a dream. we focus on the legendary band "the who". they played at woodstock and wrote a rock opera and performed at the close of the olympics in london. you remember that. take a closer look how "the who" reaches out to help teenagers in need. ♪ they're undeniably one of the greatest rock bands of all time. the "the who", for more than 40 years, roger daltrey and pete townsend of "the who"

have been entertaining fans throughout the world. ♪ but "the who" aren't your ordinary rock stars. their latest collaboration goes beyond the bounds of music and entertainment and they are launching "who cares, teen cancer america" a nonprofit organization helping teenagers and young adults deal with cancer. one dollar from each ticket sale of their current ticket tour goes towards funding the foundation. >> you have to remember that, when the teenagers gets cancer, it's at the time of your life where a spot on your nose is a big deal. >> recently, roger addressed the national press club explaining why he is so passionate about helping teens with cancer. roger, what motivates you to do exactly what you do to reach out and help teens with cancer? >> i lead a privileged life and that was built with the support of teenagers and, but

mostly because it's something that needs to be fixed, it's very easy to be fixed. and they are eour future. >> kelly: roger understands when cancer strikes anyone it's a time of dread and fear, but when a teenager is diagnosed with cancer and hospitalized, well, unique problems can arise. teens often feel isolated. >> they really have no place to go or no one to turn to to help work together, fellowship through the problems and suffer through the problems and discussing. if you spend the youthful years, alone, suffering from a terrible illness, and your parents also need support. what we've actually discovered, almost stumbling across it, is that by providing special care for teenage groups, it really does help. >> "the who" has been helping teens with cancer for 25 years now. it was then the band played benefit concerts to turn two

hospitals into the u.k. into the teen cancer trust and now, they're expanding to the u.s. >> teenagers love to be together. and they love to be together. and you know, parties used to have with all of your mates. and teenagers with the same thing, they need a little bit of space in a hospital. not a great deal, just space, where they can be teenagers, they can make a bit of noise, neck have mtv, they can have computers, they can continue their education. >> sarah, the teenage survivor of cancer helped applaud the efforts of the "the who" for teens in cancer. >> this has been shown to have beneficial effect as far as health as well. when your emotional health is better, your physical health is going to be better. and being a survivor two and a half years i firmly believe in that because if i didn't have the support that i had, i don't think i would be here

today and that's why i support teen cancer america and hope you all will joan us as well. [applaus [applause] >> well said, sarah and roger and pete as well. a year ago, ucla health system opened the first teen cancer unit in the u.s. thanks to ""who cares" between teenagers between the the ages and 13 and young adults and more units to provide a support system throughout the country. >> jamie: why wouldn't we, kelly. >> kelly: absolutely. >> jamie: they're doing more than just talking about it, that's a very inspiring story. >> kelly: going beyond the rock. >> jamie: thank you, and beyond the dream. well, tensions are rising a serious situation. israel is trading fire with militants in the gaza strip. the latest on the growing crisis, what must the u.s. do straight ahead. >> check this out: tsa acknowledging a shocking

security weakness at our nation's airport, how it could be exploited, rather, to smuggle dangerous objects on to domestic flights. we're not going to tell you exactly how to do it though. >> and former cia chief david petraeus testifying about the deadly terrorist attacks on u.s. facilities in benghazi, a member of the house intelligence committee will give his take on it and he was in the room and we'll take you inside and that's straight ahead. [ female announcer ] today, jason is here to volunteer to help those in need. when a twinge of back pain surprises him. morning starts in high spirits but there's a growing pain in his lower back. as lines grow longer, his pain continues to linger. r a long day but there's a growing pain of helping others,

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these (siren sounding) have been blaring across israel. can you imagine how frightening? it's always warning of imminent danger from incoming rockets and haven't heard them in quite some time and israel a mobilizing an army of tanks and as many as 75,000 troops near the border. meantime, the white house is also reaching to the leaders of egypt and turkey, hoping that they will be able to encourage hamas to end the violence now. kelly. >> kelly: jamie, thank you. well, there are new questions being raised about the deadly benghazi attack. former cia director david petraeus testifying on capitol hill about what the cia knew during and after the attack that killed four americans, including the u.s. ambassador. here now, republican congressman joe heck from nevada, a member of the house committee. he was in the hearing and he heard general petraeus and sir, i've got to ask you, are you satisfied with david petraeus's testimony about the

events that took the lives of ambassador chris stevens and three other americans? >> well, i am, kelly. i am he' satisfied with the testimony of general petraeus, but there's still unanswered questions that we're waiting to be answered by the administration and that is, what was known by the administration and when did they know it. general petraeus came before us on september 14th and gave his best assessment of the situation at that time and came back yesterday to reiterate many points and tell us where the inintelligence changed from when he first had come before us on september 14th, but what we do know is that the talking points that were put together and released by the cia were changed by the time they were presented on the sunday morning talk shows by ambassador rice, so the question, why were they changed, who changed them and what was the purpose. >> kelly: and that seems to be the major sticking point right now on capitol hill, where all of you are just trying to find out, who, what, when, how, and why.

and were those changed and making it classified as i understand, but who did change it. when you do find out how will that help you move forward? >> well, i think it will help us bring accountability and transparency to the process and plus help bring closure to the four families that have lost those u.s. public servants. i mean, they deserve to know the answers in a much more expedient fashion and complete fashion than has been given to them. the association where did things change from the 14th of september to two days later to the sunday morning talk shows when we know that there was information gleaned from the u.s. citizens that were evacuated from the temporary mission facility that was not reflected. we know there were multiple motivations for the attack, but yet, the administration seemed to want to concentrate on this youtube video without giving a more complete picture of what some of the other motivations may have been and those are the answers that we're searching for. >> kelly: congressman, one of the concerns that you have, of course, when u.n. ambassador susan rice kept talking about

spontaneous reaction to that anti-islam video, which was only a teaser, actually, a trailer, so having said that, now that you're moving forward, what does this entire matter say about the status of our intelligence community and the fact that someone went in and changed the status of what the intelligence community had concluded and that was in fact on the initial report, and david petraeus himself who also visited libya, the only u.s. leader who actually go there, a top official and return and say on his initial reaction he thought and knew that it was a terrorist attack? >> well, and that's the issue, and look, our intelligence community did a phenomenal job in putting together and synthesizing the information. this is no indictment on intelligence community. what was released from cia headquarters on friday, unclassified talking point memo to the point it was changed to the sunday morning talk shows there's a gap of 48 hours we need to account for

and understand why it was changed. >> kelly: not to interrupt you you said to understand why it was changed. the democrats say it was changed to protect classified information and as you know some colleagues in the republican parties are saying no, no, no, it was politically motivated. where is the answer? >> well, i think the answer, one has to come from ambassador rice, who briefed ambassador rice, what was she given and what did she know about the information she was asked to relay on the sunday morning talk shows, and the other part comes from the administration, from the national security council. why was the talking point memo that was initially released from the cia after it went through its intelligence community process, why were certain things taken out and why was there such an emphasis on this youtube video as opposed to the multiple other motivations that also could have sparked the attack. >> kelly: and congressman, the bottom line, we're two months after this event took place on september 11th when our u.s. ambassador and three other americans were killed in this attack, and we still have no

answers. we still have more questions. so, how do we move forward? how do we bring closure to the families? >> certainly, we continue through the committee process, in congress, and not just in the the house intelligence community, but the foreign affairs committee which has jurisdiction over the department of state and we need to continue to search for the answers and ambassador rice is going to need to answer the questions, who briefed her, how was she briefed and why was that the talking point memo she was given to present to the american public. >> kelly: certainly a lot more to do. congressman joe heck of nevada, thank you for joining us this afternoon, sir, good day to you. >> thank you. >> jamie: well, meanwhile, i'm always careful reporting these stories because i don't want to give anything to the bad guys, but a tsa official is now confirmed there's a vulnerability in our nation's airport security and if it were to be exploited it could make it easier for passengers to take potentially dangerous items on board their flights.

dominique di-natale live at lax, the airport in los angeles, california. tell us what's going on. all right, a little bit of a satellite problem, having nothing to do with the story, and basically, there's a boarding pass issue, we'll bring that to you shortly. kelly. >> kelly: i want to hear that because i fly a lot. >> jamie: absolutely, the holidays are coming. >> kelly: we'll try to get back to dominique as soon as we can. scientists now say they've identified a rare mutation of a gene that could increase your risk of-- for alzheimer's and how this could change the fight against the terrible disease. >> jamie: also, millions of americans will reach retirement next year. well, some financial experts say leaving the work force could be for them a big mistake. that news ahead. i'm a conservative investor. i invest in what i know. i turned 65 last week. i'm getting married. planning a life. there are risks, sure. but, there's no reward without it.

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>> welcome back, everybody. if you have the option to

retire next year, there are some financial experts that are saying, don't do it. questions about taxes, the markets, and the health care costs could mean a rough road ahead for our seniors. joining us now, jonathan hoenig of portfolio manager for the capitalist pig hedge fund and a regular on cashin' in. jonathan. >> great to be with you. >> jamie: we're not of that age yet, many people are and next year may not be the year for them. how come? >> yeah, nearly 7 million folks on the verge of retirement and unfortunately, jamie they've been screwed, screwed by government policy and policies in fact continue to this day. for one thing of course the safety net they've been promised not going to be there or there in a much reduced fashion, but the taxes are most destructive. folks who saved their whole life paid taxes and trying to live off the proceeds of investments, the taxes go up

to 44%? that's literally food out of retiree's mouth. >> it's startling to stunning invested put away whether conservatively or taking risk and now the same profits, they may be taxed at a rate may not be paying what they may have paid when earning salary. will be treated as ordinary income? >> indeed. and as you've pointed out. how is someone either currently retired or on the verge of retirement and i've got to say if i was considering retiring i'd probably put it off for a couple of years, because of that uncertainty. it's not economic uncertainty that's got the markets down so dramatically since the election, it's political uncertainty. a trillion dollars on the sidelines, wondering what's my tax rate going to be. that's applicable not just to an old gentleman or an old lady on the verge of retirement, but businesses, people with hundreds of billions of dollars, waiting it create plans and hiring folks, none of that can be done with the uncertainly the government created. >> jamie: we've seen it the

past couple of years, a lot of money keeping it on the sidelines and businesses not hiring, and they don't have the answers yet. could it change? next year may not be the year. what about the year after? is it a cumulative effect? >> i think unfortunately, the biggest thing that's cumulative is inflation, put yourself in the pants of an older person on the verge of retirement. they're seeing their dividends, their income going down, and yet, their costs go up. not just for stuff like gas and milk, et cetera, but of course, health care. i mean, the average retiree now is going to need a quarter of a million dollars put away just it cover their health care, and that's up about 50% in just the last couple of years and under obamacare is likely to go up even more. >> jamie: i really like, jonathan when you come on with me you give me specifics and numbers, let me add something to the numbers you presented. a quarter of million dollars just to pay for obamacare for the seniors. and what about if social security goes away? >> well, i mean, it's a great point and i think it's exactly why the notion of the safety

net, which a lot of folks have believed in and paid into and now they're told late in their life, maybe the safety net isn't so safe after all. i mean, the hoards of extreme income in greece, the benefits promised slashld entirely and as long as our government talks about raising taxes and cutting entitlements and reining them back and insolvent for the near future, a lot of folks who planned on using money that simply isn't there. >> jamie: finally, i don't want to be debby downer and leave folks hanging off our own cliff. is there anything they can do about it before the end of the year? >> i think more than anything, folks, in my opinion need to take a very cautious approach. i mean, frequently we look at the terrible headlines and the economy remains stagnant and quite depressed and people have a tendency say all or none. all in stocks or all out of stocks, i think you need to take so much more, somewhat more of a measured approach and not make investing an all

or nothing decision whether it's stocks, bonds, gold or cash. >> jamie: don't ignore it, open up the statements, make the calls. thanks, jonathan. >> as painful as it is. >> jamie: happy holidays to you. >> you, too, jamie. >> jamie: kelly. >> kelly: a heart felt holiday homecoming for a group of brave americans. 60 soldiers from the army national guard returning to michigan from afghanistan, reuniting with loved ones. >> it was-- the experience was, shall say awesome, but it was an experience that we won't soon forget, so-- >> we had to tell them. be careful with our guys. >> oh, yeah, yes, yeah, it's still dangerous and hazardous area that a lot of things happen and do the best we can to be as safes we can over there and hopefully everybody comes home safe. >> kelly: and that's the key, everybody coming home safe and the emotional homecoming by the way was full of tears and

plenty of hugs, we didn't see those hugs and tears there, but i love those home comings. >> jamie: i'm sending one, okay? guys and girls, thank you so much for all you do to keep us safe here at home. all right, well, moving on, we have some interesting information, scientists made a discovery that could possibly determine your real risk of developing alzheimer's. that's next and we'll talk to a member of our fox medical a-team. stick around: [ clock ticking ] [ male announcer ] there's a better way... v8 v-fusion. vegetable nutrition they need, fruit taste they love. could've had a v8. or...try kids boxes! well, having a ton of locations doesn't hurt. and my daughter loves the santa. oh, ah sir. that is a customer. let's not tell mom. [ male announcer ] break from the holiday stress. fedex office.

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>> fox news alert. we're monitoring a tense situation in israel at this hour and we have some new video into the fox news room from israel and an apartment in the city of ashta suffering a direct hit by a hamas missile we're told. very heavy damage as you can see, fortunately, no one injured, but an israeli army spokesman speaking when sirens started going off. watch this. >> we are ready to go on. we're ready to protect all the people here no matter what it takes, if it takes a week, we have to help all people. we have more than 1 million people under fire now. and this is the place we have to protect. >> and again (siren sounding) >> let's go, let's go!. >> jamie: happening every day all day, this is the fourth

day that folks going about their business in israel are hearing those sirens, frightening scenes as they make their way to safety. the army spokesman there doing his part to make sure the folks in that area did. we're going to keep an eye all day for you and bring any new video or updates, kelly as we were talking about earlier. some of these were averted from tel aviv, coming from hamas and israel taking preventive actions. >> kelly: it's difficult seeing the images and hearing the sirens and imagining what it's like for the people living there and we talked to leland vittert and explaining that the atmosphere is one of caution, obviously, but the atmosphere among the civilians is one of what do we do next? we look for a place to hide our families and bunker down and hunker down to protect ourselves. fortunately shall the iron dome seems to be working. >> jamie: that's what they are he' doing at this hour. ♪ >> well, a possible medical

break through, scientists identifying a rare mutation in the gene that could significantly increase your risk for the most common form of alzheimer's disease. what could this mean for patients? dr. david samati a-team and chief of robotics mount sinai medical center. and shed some light on the mutations. it's getting down to the genes and might be able to determine a marker for someone to have alzheimer's. >> yes, kelly, actually, if you look at the topics that we cover, especially on saturdays, alzheimer's happens to be one of the most common topics that we have reviewed here, because there's a lot of research going on and we're getting closer and closer to possible cure, we're not quite there yet. now, as you know, alzheimer's is a very common disease. every family has one member who for some reason has cognitive impairment, lose their memory, forget where they are, may the not come back and affecting us over 5

million have people. 170 billion. and the answer to your question, if you look at the last two decades we've gone from understanding that this is a reality, to really understanding on the imaging that there are on mri's and cat scans, there are lesions on the white matter on the brain that could cause this, we had a segment not too long ago we talked about beta amyloid, plaques that kind of block the formation to go from one side of the brain to another one and they freeze their talking and thinking and all of a sudden they forget. so we've come a long way and now we're coming closer and closer to the secrets and decoding the the genes. what they're finding out british scientists, after looking at over 2000 patients and looking at their genes, they've come up with a new finding called tren 2, tren 2 is the new gene that a lot of patients with alzheimer's has it. it's interesting, as we think and as we get older, there's a lot of debris around our brain just like anything else. there are some cells, almost

like cleaning ladies that have to go around? >> sure. >> and clean up the debris this gene is responsible for those cells to clean up. if you don't clean up, you're going to get the plaques and therefore going to get alzheimer's. why this is important, kelly, is now the drug companies, because we understand this gene, we can create something to push that gene or try to interfere with this whole system to cure alzheimer's, very, very exciting. >> kelly: so, that's a potential break through because if you can determine that marker, that genetic mutation, could you possibly prevent the alzheimer's from taking place in that patient. >> at least slow it down. >> great news. we've gone from macro scopic to microscopic and gene level and it's a huge advancement on the field and of course more and more study need to be done. but if we understand the genetic part of this, we can break the code and really help millions and millions of people out there. >> kelly: yeah, and you have pointed out rightly he so, how

alzheimer's is such a dreadful thing because it takes away your cognitive skills and your memory, you lose some of the most precious things you've had in life and that's your memories, but a lot of people call it the long goodbye because it's so hard for families to see the regression or the loss of memory. >> yes, this is a devastating part of it is that alzheimer's not only just affect those patients, who don't really know what goes on, but everyone in their family and surrounding them and so this is really the-- would be the cure for the entire family and for them to watch, seeing one of their elderly grandparents, grandma, grandfather to go through this, it's a very painful process, so, i'm really excited about this and every time we're bringing this news and this came up this week, we're getting closer and closer and so that's the beauty of science and where they love it. >> i love any physician that treats the patient and the family because it is a cooperative effort. thank you, there's going to be a lot more medical stories

when the doctor joins us, covering all of them. you can watch he and dr. mark segal every sunday on sunday house call. look at that you've got your own promo, i'm going to be there, too, 10:30 eastern tomorrow morning and find them, also, on facebook. facebook.com/sunday house call or you can tweet them. they might write you back directly after a congratulations on house call growing this way. >> thank you, jamie, we're fortunate sof a lot of patients and fans who have really been giving back to us and a pleasure to bring you the latest news. >> kelly: you deserve it because you give out great information. >> jamie: got to go with six seconds left. >> jamie: i'm jamie colby. >> kelly: i'm kelly wright. the journal editorial report is next. >> jamie: bye everybody. [ engine revs ] ♪ [ male announcer ] oh what fun it is to ride. get the mercedes-benz on your wish list at the winter event going onow --

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